Our mission is to discover and develop new medicines based on novel metabolic targets in disease-causing bacteria, lymphocytes, and cancer cells.
The human body is a complex and heterogeneous system. Despite this, a century of biological discovery efforts have relied on empirically optimized cell culture conditions that do not reflect this complexity. These legacy conditions can mask metabolic adaptations that support the rapid proliferation of bacterial cells, lymphocyte populations, and cancer metastases. Octagon's discovery approach can identify metabolic targets involved in these cellular adaptations, using a novel platform that combines biological insights with computational modeling of metabolic networks.